Basic Information
VIS ID
TVIS44016751
Fusion event
HTLV-1-VIPR2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q36.3
Reference genome
GRCh37/hg19
Start
158893687/159100996 (Hg38)
End
158893687/159100996 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7I
Target gene
VIPR2
Nearest miRNA
hsa-mir-10399/Upstream/509300;
Nearest TSS
ENST00000635602/Upstream/3792; ENST00000421760/Downstream/43856;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/7092, chr7-CpG: 24/Downstream/11583
Upstream sequence
cgttcccccgactgttcctgtggtagtgaacgggtctcacgagatccgatgaggcggttccgactgttcctgtgatagtgaacgggtctcacgagatccg
Downstream sequence
acgAGGCGGTTCTGActgttcccgtggtagtgaactggtctcacgagatccgaCAAggccgttcccccgactgttcctgtggtagtgaacgggtctcacg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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