Basic Information
VIS ID
TVIS44016765
Fusion event
HTLV-1-chr7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
2528349/2488715 (Hg38)
End
2528349/2488715 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA7B
Nearest miRNA
hsa-mir-339/Upstream/231138; hsa-mir-10399/Downstream/38359;
Nearest TSS
ENST00000635602/Upstream/11821; ENST00000493850/Downstream/23814;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/28223, chr7-CpG: 192/Downstream/30022
Nearby gene
GRIFIN(-12332) ;
Upstream sequence
CCGTCTTCAGGCCCAGGCCCAGGGGAGGCTGGGAATTTAGGAGCTGGAGGTATTCTTCTGAGAGGAAAGCATTTTTGATGCAAGAAGCTTTATCCAGTTC
Downstream sequence
TACACGAGCCAGTCATCTCCttcatgtattcaagcaacatttacgaatcggtcaccgtgccctgggagctgggaggccacagagaaccacgacaATCTGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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