Basic Information
VIS ID
TVIS44016774
Fusion event
HTLV-1-NPSR1-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p14.3
Reference genome
GRCh37/hg19
Start
34661632/34622020 (Hg38)
End
34661632/34622020 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
NPSR1-AS1
Nearest miRNA
hsa-mir-1183/Upstream/1888943; hsa-mir-10399/Downstream/318740;
Nearest TSS
ENST00000635602/Upstream/412494; ENST00000465305/Downstream/36219;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/542873, chr7-CpG: 203/Downstream/414504
Upstream sequence
atagttaatcaggtattggagaactgaaagtgcaaacatgagacgctgaggtagtatagaggttgtaactgcaggaagatgtaactaccccctcgagttg
Downstream sequence
gaagggcaaagagaagggactgcaattattaaaacttagatgcttacagaaggggtcccaaggaattggggtggagacctcctggaaggcattcgctgcc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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