Basic Information
VIS ID
TVIS44016842
Fusion event
HTLV-1-chr7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
97595689/97966377 (Hg38)
End
97595689/97966377 (Hg38)
Orient
+
Location type
Intronic
Target gene
CZ1P-ASNS ; OR7E38P
Nearest miRNA
hsa-mir-10525/Upstream/1896; hsa-mir-10399/Downstream/915273;
Nearest TSS
ENST00000635602/Upstream/93835; ENST00000493372/Downstream/23819;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/27560, chr7-CpG: 51/Downstream/5618
Nearby gene
CCZ1P-OR7E38P(-219) ;
Upstream sequence
AACTGACAGGCGAGACCCACAGGTGGAGAGGGCTTTATACTTCCCACCTGATGAAGAAACCCTCAGAATGGAGGAAACAATTTTAGAGAAAGAGAAAAGG
Downstream sequence
GTCCCCAAGATGGGAAGAAAACCAAATATGGCAGCAGGGAAATACATGATTATGTTAATGGTGAAGGTGTCACAACATGCAAGATGGGAGAGTTGAGAAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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