VISDB Viral Integration Site DataBase

VIS ID

TVIS44016913

Fusion event

HTLV-1-SLC25A37 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr8

Cytoband

p21.2

Reference genome

Start

End

23420504/23562991 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-7-5p ; hsa-mir-17-5p ; hsa-mir-181a-5p ; hsa-mir-181b-5p ; hsa-mir-181c-5p ; hsa-mir-181d-5p ; hsa-mir-6515-5p ; hsa-mir-6810-5p ; hsa-mir-4443 ; hsa-mir-6505-5p ; hsa-mir-636 ; hsa-mir-4652-5p ; hsa-mir-3191-3p ; hsa-mir-3144-5p ; hsa-mir-365b-5p ; hsa-mir-365a-5p ; hsa-mir-6894-5p ; hsa-mir-765 ; hsa-mir-7154-3p ; hsa-mir-766-5p ; hsa-mir-6876-5p ; hsa-mir-4476 ; hsa-mir-4735-3p ; hsa-mir-18b-5p ; hsa-mir-18a-5p ; hsa-mir-641 ; hsa-mir-3617-5p ; hsa-mir-5089-5p ; hsa-mir-4279 ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-6778-3p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-150-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-6814-5p ; hsa-mir-6504-3p ; hsa-mir-552-3p ; hsa-mir-5571-5p ; hsa-mir-582-3p ; hsa-mir-2681-5p ; hsa-mir-30a-3p ; hsa-mir-30d-3p ; hsa-mir-30e-3p ; hsa-mir-3606-3p ; hsa-mir-452-5p ; hsa-mir-4676-3p ; hsa-mir-4693-5p ; hsa-mir-4704-3p ; hsa-mir-513a-3p ; hsa-mir-513c-3p ; hsa-mir-892c-3p

Nearest miRNA

hsa-mir-124-1/Upstream/1317954; hsa-mir-10400/Downstream/1390805;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/33118, chr8-CpG: 21/Downstream/8534

Upstream sequence

ttgtcaggggcaagtataagaagaaggcaggtgacacgtgaagctttatttgctctaaaactTGAGCGATTTCATATGTCCTAAAGGAGGAGTTTTGCCT

Downstream sequence

CTTCCTTCCCAGCATGAACACTTGGCATGGTGTGTACATCTTCATTCGTTTGGTCTGGCCAACAGCCACTCGGGAGCTGAATGAGGTGTTGTGACCATGA