VISDB Viral Integration Site DataBase

VIS ID

TVIS44016916

Fusion event

HTLV-1-DPYSL2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr8

Cytoband

p21.2

Reference genome

Start

End

26390438/26532922 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-19a-3p ; hsa-mir-425-5p ; hsa-mir-320a ; hsa-mir-10a-5p ; hsa-mir-30c-5p ; hsa-mir-17-5p ; hsa-mir-224-5p ; hsa-mir-452-5p ; hsa-mir-181c-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106a-5p ; hsa-mir-130a-3p ; hsa-mir-106b-5p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-20b-5p ; hsa-mir-519c-3p ; hsa-mir-526b-3p ; hsa-mir-519b-3p ; hsa-mir-519d-3p ; hsa-mir-519a-3p ; hsa-mir-454-3p ; hsa-mir-301b-3p ; hsa-mir-944 ; hsa-mir-548t-5p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-548az-5p ; hsa-mir-125a-3p ; hsa-mir-3665 ; hsa-mir-1238-3p ; hsa-mir-670-3p ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-7111-3p ; hsa-mir-657 ; hsa-mir-539-5p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-548e-5p ; hsa-mir-4724-3p ; hsa-mir-6782-3p ; hsa-mir-548n

Nearest miRNA

hsa-mir-124-1/Upstream/1187448; hsa-mir-10400/Downstream/515931;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/17608, chr8-CpG: 147/Downstream/43934

Upstream sequence

gctatgaatattcatggtagaatctgtgtgaacatatgtttccatttctcttagttatgtatcaaggagtaaaattcctgggttatttggtatccctaat

Downstream sequence

tttttgaggaactgccaaactgtttcccaaagtggctgcactactttacattcccatcagcagtgtatgagggttagtgtatgaggtttccaacttcgcc