VISDB Viral Integration Site DataBase

VIS ID

TVIS44016929

Fusion event

HTLV-1-FUT10 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr8

Cytoband

p12

Reference genome

Start

End

33245670/33388152 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-34a-5p ; hsa-let-7c-5p ; hsa-mir-526b-5p ; hsa-mir-570-3p ; hsa-mir-4635 ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-3613-3p ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-5584-3p ; hsa-mir-148a-5p ; hsa-mir-561-3p ; hsa-mir-548at-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-3138 ; hsa-mir-769-3p ; hsa-mir-450b-3p ; hsa-mir-488-3p ; hsa-mir-505-3p ; hsa-mir-638 ; hsa-mir-4470 ; hsa-mir-4713-3p ; hsa-mir-1468-3p ; hsa-mir-202-3p ; hsa-mir-98-5p ; hsa-mir-4458 ; hsa-mir-4500 ; hsa-let-7i-5p ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-4524a-3p ; hsa-mir-6730-5p ; hsa-mir-5681a ; hsa-mir-4698 ; hsa-mir-183-5p ; hsa-mir-4796-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-548m ; hsa-mir-32-5p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-1207-5p ; hsa-mir-198 ; hsa-mir-3912-5p ; hsa-mir-4456 ; hsa-mir-4645-5p ; hsa-mir-4650-5p ; hsa-mir-4673 ; hsa-mir-4736 ; hsa-mir-4763-3p ; hsa-mir-7150

Nearest miRNA

hsa-mir-124-1/Upstream/3430804; hsa-mir-10400/Downstream/7882896;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/838769, chr8-CpG: 60/Downstream/84494

Upstream sequence

AAATTTGAAGACATTACTAAGAAGTTCATAACAATTTAAGAAAGTTTTTATAAGGATTATCCCCACCATTATTTCAGTAGTTTCTCTCTATATTAATAAG

Downstream sequence

CACATGTTTGCCAGAAAGAGAAAGAGTAAATATTAGAGCAGCAAGCAAAATGAAAATGAGTTTGAAAGTGGAGGCTGTGGAGTGTCAGTGTGAGAGGTCT