Basic Information
VIS ID
TVIS44016962
Fusion event
HTLV-1-LOC105377796 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
p23.2
Reference genome
GRCh37/hg19
Start
5894104/6036582 (Hg38)
End
5894104/6036582 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105377796
Nearest miRNA
hsa-mir-3674/Upstream/3959942; hsa-mir-10400/Downstream/585542;
Nearest TSS
ENST00000518652/Upstream/366505; ENST00000522905/Downstream/392;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/913158, chr8-CpG: 72/Downstream/369479
Nearby gene
LOC100287015(-366973) ;
Upstream sequence
AGGACAAACGAAACCCTGCGTTATGAGCACAGAGTAGGTTTCTCTTCTATTCAATCATCCACACAGACACTTGAGCATTTTTTTATATTATAGTCATGAA
Downstream sequence
ATACCAATTACATCATACACTGTAAAGAGACAGTGACCATGGACAGCCCTTGCATGTTAAGTGATGATGTGCGGGTGTCACAGAGCCTCCAGCAGCAGCG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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