Basic Information
VIS ID
TVIS44016975
Fusion event
HTLV-1-LACTB2-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
71555595/70643360 (Hg38)
End
71555595/70643360 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
LACTB2-AS1
Nearest miRNA
hsa-mir-124-1/Upstream/6264103; hsa-mir-10400/Downstream/3905183;
Nearest TSS
ENST00000518652/Upstream/29425; ENST00000519350/Downstream/768;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/34738, chr8-CpG: 66/Downstream/25455
Upstream sequence
ttgcccaggctggagtacaatggcggatcttggctcactacaacctccacctctcaggttcaagcaactctcctgcctcagcctcccgcgtagctgggat
Downstream sequence
tataggtacctgccaccacgcctgggtaatttttgtattattagtagagacagggtttcaccatgttggccaggctgatctcgaactcctgacctcaggt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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