Basic Information
VIS ID
TVIS44016990
Fusion event
HTLV-1-LOC105375931 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q21.13
Reference genome
GRCh37/hg19
Start
83380918/82468683 (Hg38)
End
83380918/82468683 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105375931
Nearest miRNA
hsa-mir-12123/Upstream/2227210; hsa-mir-10400/Downstream/8736802;
Nearest TSS
ENST00000518652/Upstream/308106; ENST00000524359/Downstream/67724;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/626442, chr8-CpG: 49/Downstream/1715841
Nearby gene
SNX16(-626397) ;
Upstream sequence
ctttataaaaaaatcaactcaaaaaatccatcaaagatggatcaaagacgtaactgtaagacctaaaaccataacagttctcaacgataacgtcaaaaaa
Downstream sequence
actcatcttgacattggctaagtcaaagagttcatgaccaagaacccaaaagcaaatgcaacaaacacaaagataaatagataggacctaattaaactaa
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate