Basic Information
VIS ID
TVIS44017016
Fusion event
HTLV-1-chr9 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
112348990/109586710 (Hg38)
End
112348990/109586710 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA9E
Nearest miRNA
hsa-let-7a-1/Upstream/75165; hsa-mir-12126/Downstream/1684446;
Nearest TSS
ENST00000422679/Upstream/88397; ENST00000465091/Downstream/54078;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/52243, chr9-CpG: 62/Downstream/53777
Nearby gene
PALM2(+54078) ;
Upstream sequence
ccattcagagatgtcccaagttgaggcaagagggctggactttctacactacctggaccagtcactgcatgtgtgctgctcccagagaggggtggtaacc
Downstream sequence
ttggatgagtagccccctttggcagagggcagtttccagggctAGTGGAGTGAGTGCCCCAGTCCTAGGTCCTCAGTCCTAGGTCCTGGAAAGGATCTGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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