Basic Information
VIS ID
TVIS44017022
Fusion event
HTLV-1-LOC105376223 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q32
Reference genome
GRCh37/hg19
Start
116412779/113650499 (Hg38)
End
116412779/113650499 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA9E
Target gene
LOC105376223
Nearest miRNA
hsa-let-7a-1/Upstream/1718330; hsa-mir-12126/Downstream/558935;
Nearest TSS
ENST00000422679/Upstream/31271; ENST00000428292/Downstream/457;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/66176, chr9-CpG: 29/Downstream/37366
Nearby gene
RGS3(+52756) ;
Upstream sequence
AGGGCCAAAGCATTGAGACTTGCTTCACCTATTGGAATGGGGTCCTGAGGATCGATGCGACACATGGCCTGCAAGTTGCCTGCAGCATGCCTGTTGGAGG
Downstream sequence
GTGAggtcagccagtctctgcttgcatagctctcggacaggaagcttactatttgctcaggcagcctgtctcatcccagcgactgtgagaaagcatcctc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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