Basic Information
VIS ID
TVIS44017028
Fusion event
HTLV-1-OR1B1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q33.2
Reference genome
GRCh37/hg19
Start
125356384/122594105 (Hg38)
End
125356384/122594105 (Hg38)
Orient
+
Location type
Intronic
Target gene
OR1B1
Nearest miRNA
hsa-let-7a-1/Upstream/473938; hsa-mir-12126/Downstream/517441;
Nearest TSS
ENST00000422679/Upstream/10721; ENST00000297913/Downstream/15810;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/246740, chr9-CpG: 42/Downstream/234031
Nearby gene
OR1Q1(+20633) ;
Upstream sequence
ttcctccatccttttgttttgagcctatgtgtgtctctgcatgtgagatgggtttcctgaatacagcacactgatgggtcttaactctttatccaatttg
Downstream sequence
ccagtctgtgtctttaattggagcatttagtccatttacatttaaagttaatattgttatgtgtgagtttgatcctgtcatgatgatgttagctggttat
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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