Basic Information
VIS ID
TVIS44017032
Fusion event
HTLV-1-GAPVD1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q33.3
Reference genome
End
128068987/125306708 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-34a-5p ; hsa-mir-98-5p ; hsa-mir-21-5p ; hsa-let-7b-5p ; hsa-mir-30c-5p ; hsa-mir-4280 ; hsa-mir-3192-5p ; hsa-mir-6510-3p ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-6888-3p ; hsa-mir-196a-3p ; hsa-mir-661 ; hsa-mir-873-3p ; hsa-mir-4522 ; hsa-mir-3120-5p ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-3187-5p ; hsa-mir-5189-5p ; hsa-mir-1285-3p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-939-3p ; hsa-mir-3664-5p ; hsa-mir-302c-5p ; hsa-mir-6873-3p ; hsa-mir-3143 ; hsa-mir-492 ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-6845-3p ; hsa-mir-136-5p ; hsa-mir-197-3p ; hsa-mir-6809-3p ; hsa-mir-3692-3p ; hsa-mir-4753-3p ; hsa-mir-1260b ; hsa-mir-1260a ; hsa-mir-6802-3p ; hsa-mir-6886-3p ; hsa-mir-942-5p ; hsa-mir-6754-3p ; hsa-mir-412-3p ; hsa-mir-1236-3p ; hsa-mir-6515-3p ; hsa-mir-1224-3p ; hsa-mir-140-3p ; hsa-mir-129-2-3p ; hsa-mir-129-1-3p ; hsa-mir-6779-3p ; hsa-mir-4687-5p ; hsa-mir-6516-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-455-3p ; hsa-mir-6807-5p ; hsa-mir-203b-3p ; hsa-mir-7158-3p ; hsa-mir-7847-3p ; hsa-mir-6880-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-6499-3p ; hsa-mir-767-5p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-6134 ; hsa-mir-1185-5p ; hsa-mir-1224-5p ; hsa-mir-30c-1-3p ; hsa-mir-30c-2-3p ; hsa-mir-3122 ; hsa-mir-3165 ; hsa-mir-3605-5p ; hsa-mir-363-5p ; hsa-mir-3656 ; hsa-mir-3679-5p ; hsa-mir-3913-5p ; hsa-mir-3915 ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-450a-1-3p ; hsa-mir-4689 ; hsa-mir-5186 ; hsa-mir-6513-5p ; hsa-mir-6745 ; hsa-mir-6788-5p ; hsa-mir-6858-5p ; hsa-mir-6888-5p ; hsa-mir-887-5p
Nearest miRNA
hsa-let-7a-1/Upstream/612910; hsa-mir-12126/Downstream/2383979;
Upstream sequence
cagcttcccaagtagctgggactgcaggtgcgcgccaccacacctggctaattttggtatttttcatagagacaaggttttgccctgttgccccaagtgg
Downstream sequence
ttttgaacttccgagctcaagcagtccacccaccttggcctcccaaagtgctgggattgcaggcatgcactaccacacccagcTCCAAGATCTTAGACTA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate