Basic Information
VIS ID
TVIS44017035
Fusion event
HTLV-1-PHYHD1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q34.11
Reference genome
GRCh37/hg19
Start
131685996/128923717 (Hg38)
End
131685996/128923717 (Hg38)
Orient
-
Location type
Intronic
Target gene
PHYHD1
Nearest miRNA
hsa-let-7a-1/Upstream/531003; hsa-mir-12126/Downstream/945888;
Nearest TSS
ENST00000422679/Upstream/1403; ENST00000424503/Downstream/3329;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/14904, chr9-CpG: 123/Downstream/23357
Upstream sequence
ttctgtcatgaaacaaggctcagtgaatatccccatatgtatatgtatatctttgatCCCCTATTGCGTAATCCTCCTAAAACAATTCCTAgctgtggct
Downstream sequence
cacgtctgtaatcccaatccactttgtgatgccaaggtgggaggatcgcttgtgcacaggagttcaagaccagcttgggcaatatagcaagactccttct
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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