Basic Information
VIS ID
TVIS44017054
Fusion event
HTLV-1-chr9 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
14453344/14453346 (Hg38)
End
14453344/14453346 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-101-2/Upstream/8445442; hsa-let-7a-1/Downstream/4119960;
Nearest TSS
ENST00000422679/Upstream/54363; ENST00000635735/Downstream/133980;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/103830, chr9-CpG: 56/Downstream/239686
Nearby gene
NFIB(-54362) ;
Nearest cancer related gene
NFIB(OG, -54362) ;
Upstream sequence
AACAAACATTGGCAGGTTTCTCATTCTGTGTTTAACTTTGACATGAAGCTAGTCTGTCATGTTTGAAGATCAAATGAGATTTCTGCCAACCCACTCCTAG
Downstream sequence
ATAGGGAGGATTTATCTGCAACCACACTATGATGTTCCCTTAATACTTTTCAAAAATACAAGTGCTTACATCCTAATAGGTTTTTAGCTTAAGATCTAAT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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