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TVIS44017073
Basic Information
VIS ID
TVIS44017073
Fusion event
HTLV-1-B4GALT1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
33165477/33165479 (Hg38)
End
33165477/33165479 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA9C
Target gene
B4GALT1
miRNAs that regulate target gene
hsa-mir-124-3p
;
hsa-mir-155-5p
;
hsa-mir-128-3p
;
hsa-mir-122-5p
;
hsa-mir-1-3p
;
hsa-mir-16-5p
;
hsa-mir-484
;
hsa-mir-15b-5p
;
hsa-mir-18a-5p
;
hsa-mir-185-5p
;
hsa-mir-4306
;
hsa-mir-1207-5p
;
hsa-mir-4763-3p
;
hsa-mir-550a-5p
;
hsa-mir-550a-3-5p
;
hsa-mir-1271-3p
;
hsa-mir-550b-2-5p
;
hsa-mir-6889-3p
;
hsa-mir-125a-5p
;
hsa-mir-4668-5p
;
hsa-mir-766-5p
;
hsa-mir-4533
;
hsa-mir-6722-3p
;
hsa-mir-1909-3p
;
hsa-mir-4490
;
hsa-mir-940
;
hsa-mir-6893-5p
;
hsa-mir-6808-5p
;
hsa-mir-6876-5p
;
hsa-mir-4476
;
hsa-mir-6859-5p
;
hsa-mir-3916
;
hsa-mir-3125
;
hsa-mir-6891-5p
;
hsa-mir-3173-3p
;
hsa-mir-4511
;
hsa-mir-582-3p
;
hsa-mir-7-2-3p
;
hsa-mir-7-1-3p
;
hsa-mir-5688
;
hsa-mir-495-3p
;
hsa-mir-583
;
hsa-mir-6773-5p
;
hsa-mir-6724-5p
;
hsa-mir-4792
;
hsa-mir-296-5p
;
hsa-mir-4687-3p
;
hsa-mir-7974
;
hsa-mir-4312
;
hsa-mir-4641
;
hsa-mir-1233-3p
;
hsa-mir-1225-3p
;
hsa-mir-6774-5p
;
hsa-mir-635
;
hsa-mir-6504-5p
;
hsa-mir-3064-5p
;
hsa-mir-3189-3p
;
hsa-mir-4726-3p
;
hsa-mir-125a-3p
;
hsa-mir-4712-3p
;
hsa-mir-598-3p
;
hsa-mir-30d-5p
;
hsa-mir-30e-5p
;
hsa-mir-30c-5p
;
hsa-mir-30b-5p
;
hsa-mir-30a-5p
;
hsa-mir-19b-3p
;
hsa-mir-19a-3p
;
hsa-mir-195-5p
;
hsa-mir-15a-5p
Nearest miRNA
hsa-mir-101-2/Upstream/56714; hsa-let-7a-1/Downstream/302390;
Nearest TSS
ENST00000422679/Upstream/88820;
ENST00000426270/Downstream/1496;
Nearest CpG islands
None/Target,
chr9-CpG: 64/Upstream/88702
,
chr9-CpG: 126/Downstream/1223
Upstream sequence
catgtctcaagtcagacacttagcagcaaggcagagtcCATTTCATTTTATGGGACTAGTCTGCTTCCCAGAATAATCATCAAATGCAAAGGAATTTAAT
Downstream sequence
TATCTGCTTAAAAAAACAAGCCCCCATTATTACCACAGTTCACGTCTGACCAATTCCAAGATGTTCTTCCCAAACTTGATATGAACACATTGACGCAATT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Sample Information
×
Sample name
HAM/TSP#1
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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