VISDB Viral Integration Site DataBase

VIS ID

TVIS44017074

Fusion event

HTLV-1-AQP3 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr9

Cytoband

p13.3

Reference genome

Start

End

33445825/33445827 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-615-3p ; hsa-mir-874-3p ; hsa-mir-185-5p ; hsa-mir-6882-3p ; hsa-mir-4641 ; hsa-mir-6893-3p ; hsa-mir-370-3p ; hsa-mir-4789-3p ; hsa-mir-8485 ; hsa-mir-4643 ; hsa-mir-6809-3p ; hsa-mir-4753-3p ; hsa-mir-1236-3p ; hsa-mir-6515-3p ; hsa-mir-653-5p ; hsa-mir-6869-5p ; hsa-mir-877-5p ; hsa-mir-889-3p ; hsa-mir-3163 ; hsa-mir-3159 ; hsa-mir-6859-5p ; hsa-mir-3916 ; hsa-mir-3125 ; hsa-mir-1277-5p ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-548n

Nearest miRNA

hsa-mir-101-2/Upstream/337062; hsa-let-7a-1/Downstream/22042;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/154822, chr9-CpG: 41/Downstream/1621

Upstream sequence

CCTCACACCAGGTATCTCAGAGAAAGGGGCTTTCCTCACCCCAAAGCCAACCCTGATTCTGCCACTGCAGGCCTAGGCTCCCAACACGCAGGTAGGCAGG

Downstream sequence

CAGGCACTCACCCACTACAAAGGGATCCCCAGGCCTGCCCCTCCAGTTCATGCAGTCCTTGAAGTTCTGCTTCTCACTGATATCCAATACCTCACATCCA