VISDB Viral Integration Site DataBase

VIS ID

TVIS44017086

Fusion event

HTLV-1-PTAR1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr9

Cytoband

q21.12

Reference genome

Start

End

72345665/69730749 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-210-3p ; hsa-mir-1-3p ; hsa-mir-7-5p ; hsa-mir-21-5p ; hsa-mir-15b-5p ; hsa-mir-30c-5p ; hsa-mir-15a-5p ; hsa-mir-16-2-3p ; hsa-mir-195-3p ; hsa-mir-4662a-3p ; hsa-mir-4803 ; hsa-mir-379-3p ; hsa-mir-380-3p ; hsa-mir-411-3p ; hsa-mir-4495 ; hsa-mir-374a-5p ; hsa-mir-155-5p ; hsa-mir-135b-3p ; hsa-mir-4325 ; hsa-mir-7703 ; hsa-mir-1206 ; hsa-mir-8065 ; hsa-mir-891b ; hsa-mir-6783-5p ; hsa-mir-4703-5p ; hsa-mir-3942-5p ; hsa-mir-32-5p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-25-3p ; hsa-mir-1827 ; hsa-mir-4704-3p ; hsa-mir-449c-5p ; hsa-mir-34b-5p ; hsa-mir-2682-5p ; hsa-mir-4752 ; hsa-mir-8056 ; hsa-mir-3691-5p ; hsa-mir-376c-5p ; hsa-mir-376b-5p ; hsa-mir-4657 ; hsa-mir-4491 ; hsa-mir-8066 ; hsa-mir-599 ; hsa-mir-3161 ; hsa-mir-1266-3p ; hsa-mir-4793-5p ; hsa-mir-5582-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-30e-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30a-5p

Nearest miRNA

hsa-mir-101-2/Upstream/28496914; hsa-let-7a-1/Downstream/1079226;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/57584, chr9-CpG: 74/Downstream/28743

Upstream sequence

ctgtgctcccattgtattctgatgctttgtaattgttggtctactttctcaactagattttcaatttgttgagagcaaacactttgttttactGCGTATA

Downstream sequence

CAGGACAGTCGGTGGGTATGATAGGGTTTTATACTTTTTCATCAATAAATTGCACGGAGTTGATCAAGCAAACTGGTAGCCAATTTTCTATCTCTGGAGA