Basic Information
VIS ID
TVIS44017092
Fusion event
HTLV-1-C9orf57 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q21.13
Reference genome
GRCh37/hg19
Start
74668822/72053906 (Hg38)
End
74668822/72053906 (Hg38)
Orient
+
Location type
Intronic
Target gene
C9orf57
Nearest miRNA
hsa-mir-101-2/Upstream/1243822; hsa-let-7a-1/Downstream/11915842;
Nearest TSS
ENST00000422679/Upstream/142104; ENST00000477618/Downstream/6699;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/142143, chr9-CpG: 71/Downstream/95419
Upstream sequence
gtggattgttattcatcagtggtatactgaacgtacttgttggcaactgaattttttcccactcaatatgtttagagattcctccatgttaacaagggga
Downstream sequence
tctggttcattttgagtgttgcatagcactccatgacctgcatgtaacacagttgaatgaatagttccctatagatgaacgtttaggtcatttctttttg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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