Basic Information
VIS ID
TVIS44017109
Fusion event
HTLV-1-CTSL3P integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q21.33
Reference genome
GRCh37/hg19
Start
90397967/87783052 (Hg38)
End
90397967/87783052 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
CTSL3P
Nearest miRNA
hsa-mir-101-2/Upstream/3813195; hsa-let-7a-1/Downstream/962784;
Nearest TSS
ENST00000422679/Upstream/56912; ENST00000325643/Downstream/70390;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/56425, chr9-CpG: 40/Downstream/41638
Upstream sequence
CACCATGGCTGGATTCAGGCAACAGTGTTTTTTCattcattcattctgaaaaattttattgagtctctttaagtcaggtcttgtgctgaggaatcaatga
Downstream sequence
tgaaccaacactgagacattccctgtgctGGAGAagcctgaatgtgtagaaggctctaccatctagatttgtgtaagttcactctatgatagtcacacaa
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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