Basic Information
VIS ID
TVIS44017117
Fusion event
HTLV-1-DMRT1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
p24.3
Reference genome
GRCh37/hg19
Start
949788/949788 (Hg38)
End
949788/949788 (Hg38)
Orient
-
Location type
Intronic
Target gene
DMRT1
Nearest miRNA
hsa-mir-1302-9/Upstream/919507; hsa-let-7a-1/Downstream/3900509;
Nearest TSS
ENST00000422679/Upstream/107074; ENST00000417254/Downstream/27176;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/106424, chr9-CpG: 98/Downstream/19809
Upstream sequence
aaactttgtaccctttaagcacttccctgttttccctttctctcaggccctgtagccaccattctactctgcttctgtgggtttggctattttagatttc
Downstream sequence
tcatgtaagtggaaatcacagagtacttgtccttccgtgtctggcttatttcacttagcacagtgtcctccaggttcattccgttgcaaatggtaagatt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate