Basic Information
VIS ID
TVIS44017125
Fusion event
HTLV-1-TMOD1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q22.33
Reference genome
GRCh37/hg19
Start
100280412/97518130 (Hg38)
End
100280412/97518130 (Hg38)
Orient
-
Location type
Intronic
Target gene
TMOD1
miRNAs that regulate target gene
hsa-mir-412-3p ; hsa-mir-544a ; hsa-mir-1185-2-3p ; hsa-mir-1185-1-3p
Nearest miRNA
hsa-let-7a-1/Upstream/154449; hsa-mir-12126/Downstream/711019;
Nearest TSS
ENST00000422679/Upstream/294; ENST00000375175/Downstream/37305;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/15195, chr9-CpG: 116/Downstream/114928
Upstream sequence
GCTTCCACACGTCCGCGATGGGCCCCCCAGCTTCTCTTCACCACAGCTGCCCCAACACCTGCCCCATCTTCTCCTCCTGTCCCAGTTCCATGTtattatg
Downstream sequence
ggttggattgtgtccccaaaaaagctgcacctgtgaatgtgacctgtgaatgtgataaggtccttagggaagccctaatgcaatatgactgctgtcctca
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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