VISDB Viral Integration Site DataBase

VIS ID

TVIS44017147

Fusion event

HTLV-1-PLEKHA1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr10

Cytoband

q26.13

Reference genome

Start

End

124163613/122404097 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

FRA10D ; FRA10F ; FRA10A ; FRA10B

Target gene

miRNAs that regulate target gene

hsa-mir-590-3p ; hsa-mir-335-5p ; hsa-mir-124-3p ; hsa-mir-93-5p ; hsa-mir-32-5p ; hsa-mir-26b-5p ; hsa-mir-21-5p ; hsa-mir-769-5p ; hsa-mir-25-3p ; hsa-mir-92a-3p ; hsa-mir-125b-2-3p ; hsa-mir-190a-3p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-338-3p ; hsa-mir-92b-3p ; hsa-mir-634 ; hsa-mir-1179 ; hsa-mir-4310 ; hsa-mir-5011-5p ; hsa-mir-5697 ; hsa-mir-7157-5p ; hsa-mir-371a-5p ; hsa-mir-372-5p ; hsa-mir-373-5p ; hsa-mir-616-5p ; hsa-mir-630 ; hsa-mir-371b-5p ; hsa-mir-6883-3p ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-103a-3p ; hsa-mir-107 ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-3607-5p ; hsa-mir-4524a-5p ; hsa-mir-5197-5p ; hsa-mir-4524b-5p ; hsa-mir-6838-5p ; hsa-let-7e-3p ; hsa-mir-545-3p ; hsa-mir-570-5p ; hsa-mir-3148 ; hsa-mir-548ag ; hsa-mir-548ai ; hsa-mir-4477a ; hsa-mir-4678 ; hsa-mir-548ba ; hsa-mir-3973 ; hsa-mir-124-5p ; hsa-mir-3607-3p ; hsa-mir-1206 ; hsa-mir-3650 ; hsa-mir-7154-5p ; hsa-mir-411-5p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-4272 ; hsa-mir-4470 ; hsa-mir-548o-3p ; hsa-mir-1323 ; hsa-mir-1278 ; hsa-mir-646 ; hsa-mir-503-5p ; hsa-mir-1183 ; hsa-mir-101-3p ; hsa-mir-433-3p ; hsa-mir-6853-3p ; hsa-mir-4455 ; hsa-mir-8060 ; hsa-mir-514b-5p ; hsa-mir-513c-5p ; hsa-mir-454-5p ; hsa-mir-6866-3p ; hsa-mir-188-5p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-7977 ; hsa-mir-4483 ; hsa-mir-1293 ; hsa-mir-6766-5p ; hsa-mir-6756-5p ; hsa-mir-6745 ; hsa-mir-363-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-1273f ; hsa-mir-4708-5p ; hsa-mir-6088 ; hsa-mir-4770 ; hsa-mir-143-3p ; hsa-mir-383-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929

Nearest miRNA

hsa-mir-107/Upstream/2445505; hsa-mir-202/Downstream/12868;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/28680, chr10-CpG: 225/Downstream/56725

Upstream sequence

TTTTTATAGTGCTTCCTTACTCCTTAGAAATCTCCAGATGATGGCAGTGAAGAAtattctataccaagcactgtgttagtttctttacatatatgatcgt

Downstream sequence

cacctcttaaggaggtggaatgagtgacattcccatttcacagatgaggagtatcgggctcagagaaattaaataatgtttaaaagatgatattgcttgt