Basic Information
VIS ID
TVIS44017150
Fusion event
HTLV-1-chr10 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q26.13
Reference genome
GRCh37/hg19
Start
126898424/125209855 (Hg38)
End
126898424/125209855 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA10D ; FRA10F ; FRA10A ; FRA10B
Nearest miRNA
hsa-mir-107/Upstream/176985; hsa-mir-202/Downstream/609885;
Nearest TSS
ENST00000439456/Upstream/47476; ENST00000431861/Downstream/364516;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/47097, chr10-CpG: 54/Downstream/18152
Nearby gene
CTBP2(-48800) ;
Nearest cancer related gene
CTBP2(OG, -48800) ;
Upstream sequence
TCGATCCTGGGAAGCTGACTCCCTGGTCATATGATGGAGGTCAAGGCTGTTGTTTCTGGGGCCTGTGGTTGGGAAAGATTCCTCAAGAATCCAGAAGAGA
Downstream sequence
ATGTGAGATTAACTATTTTTCCTATAATAGTTAACAGAACTTCATTGAGGCTGGTGGAACAAGAAGCCACAGAAAGAAGACAGTTTTCTAGAAATGTCTT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate