Basic Information
VIS ID
TVIS44017151
Fusion event
HTLV-1-chr10 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q26.13
Reference genome
GRCh37/hg19
Start
127274134/125585565 (Hg38)
End
127274134/125585565 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10F ; FRA10A ; FRA10B
Target gene
LOC102724793 ; TEX36
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-107/Upstream/552695; hsa-mir-202/Downstream/234175;
Nearest TSS
ENST00000439456/Upstream/11120; ENST00000530795/Downstream/97541;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/356808, chr10-CpG: 84/Downstream/133493
Nearby gene
TEX36-AS1(No orient, 7120)
Upstream sequence
gcctgtcatagaaaacaaaaatcctctcccccaaggtggatcaaagaaactagaactcctctaccccaaagctagccataaaatatgggaaggtcactct
Downstream sequence
gatctctctttcccctgaaagccctcatgggacaggtgtcctaccctatgtgtagaagggaaggaaagtcttacagagacagagaaaagaatcctaacaa
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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