Basic Information
VIS ID
TVIS44017166
Fusion event
HTLV-1-RSU1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p13
Reference genome
GRCh37/hg19
Start
16761441/16719442 (Hg38)
End
16761441/16719442 (Hg38)
Orient
-
Location type
Intronic
Target gene
RSU1
miRNAs that regulate target gene
hsa-mir-34a-5p ; hsa-mir-7-5p ; hsa-mir-409-3p ; hsa-mir-409-5p
Nearest miRNA
hsa-mir-1265/Upstream/2282781; hsa-mir-107/Downstream/1125665;
Nearest TSS
ENST00000439456/Upstream/197437; ENST00000497849/Downstream/97941;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/197722, chr10-CpG: 68/Downstream/97648
Upstream sequence
TTCAAAATCATTCTTACAGCAATCCAGTTTCTTTTCCAGTCCCTTTCCATCAGACAATGGTGGCTCACTTGTATCACCCAAACACACCATGGGCTGTCGC
Downstream sequence
GCTTCTTCACCTACCCAATACCCTCTTCTCCCCTCTGCTTCCCAAAACGTAACTTATTTGCtgtcacctcttcagagacgcctcctggatgtctccacta
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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