Basic Information
VIS ID
TVIS44017177
Fusion event
HTLV-1-SVIL-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p11.23
Reference genome
GRCh37/hg19
Start
29748029/29459100 (Hg38)
End
29748029/29459100 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
SVIL-AS1
Nearest miRNA
hsa-mir-1265/Upstream/1169750; hsa-mir-107/Downstream/85904;
Nearest TSS
ENST00000439456/Upstream/167175; ENST00000375322/Downstream/22555;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/48985, chr10-CpG: 234/Downstream/276043
Upstream sequence
ttttttttgtagagactgggtcttgctatactgcttaggctggtctcaaacttctggcctcaagcgatcctcctgctgggattacaggtgtgaaccacca
Downstream sequence
cacttgaccCCAAAttttgttattttttagagacagtgtctcactgtaacccaggctggagggcagtggctcaatcatagctctctgcagccttaaactc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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