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TVIS44017191
Basic Information
VIS ID
TVIS44017191
Fusion event
HTLV-1-ZNF487 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
43937414/43441966 (Hg38)
End
43937414/43441966 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA10G
Target gene
ZNF487
miRNAs that regulate target gene
hsa-mir-629-3p
;
hsa-mir-6867-3p
;
hsa-mir-4713-5p
;
hsa-mir-296-3p
;
hsa-mir-4262
;
hsa-mir-181d-5p
;
hsa-mir-181c-5p
;
hsa-mir-181b-5p
;
hsa-mir-181a-5p
;
hsa-mir-2355-3p
;
hsa-mir-4646-3p
;
hsa-mir-4433b-5p
;
hsa-mir-376b-3p
;
hsa-mir-376a-3p
;
hsa-mir-4449
;
hsa-mir-664a-3p
;
hsa-mir-329-5p
;
hsa-mir-4748
;
hsa-mir-4464
;
hsa-mir-6818-5p
;
hsa-mir-4452
;
hsa-mir-3191-5p
;
hsa-mir-1257
;
hsa-mir-4653-5p
;
hsa-mir-3921
;
hsa-mir-146a-3p
;
hsa-mir-331-3p
;
hsa-mir-6801-3p
;
hsa-mir-6810-3p
;
hsa-mir-5571-5p
;
hsa-mir-498
;
hsa-mir-4279
;
hsa-mir-4284
;
hsa-mir-4772-3p
;
hsa-mir-1976
;
hsa-mir-3653-5p
;
hsa-mir-1304-3p
;
hsa-mir-6747-3p
;
hsa-mir-6727-3p
;
hsa-mir-4722-3p
;
hsa-mir-4726-3p
;
hsa-mir-6764-5p
;
hsa-mir-1915-3p
;
hsa-mir-6840-3p
;
hsa-mir-4277
;
hsa-mir-6890-3p
;
hsa-mir-1306-5p
;
hsa-mir-3613-3p
;
hsa-mir-3672
;
hsa-mir-371a-5p
;
hsa-mir-371b-5p
;
hsa-mir-372-5p
;
hsa-mir-373-5p
;
hsa-mir-4797-5p
;
hsa-mir-5586-3p
;
hsa-mir-5692a
;
hsa-mir-616-5p
;
hsa-mir-6864-3p
;
hsa-mir-759
;
hsa-mir-873-3p
Nearest miRNA
hsa-mir-1265/Upstream/444285; hsa-mir-107/Downstream/1722048;
Nearest TSS
ENST00000439456/Upstream/4808;
ENST00000596267/Downstream/9954;
Nearest CpG islands
None/Target,
chr10-CpG: 68/Upstream/4742
,
chr10-CpG: 69/Downstream/13470
Upstream sequence
gtgagccaccatgcccagccttcccctgtctttacatataaattttagaataaggttgtttataaaatatcttgctgtggttGGCCATGTAggcttatgc
Downstream sequence
ctgtaatctgagtgctttgggaggtagaggcgggaaaatcaaagtcaggagttcaagaccagtctggccaatgtagctaaccctgtctgtacgaaaaaaa
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Sample Information
×
Sample name
HAM/TSP#1
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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