Basic Information
VIS ID
TVIS44017195
Fusion event
HTLV-1-chr10 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q11.22
Reference genome
GRCh37/hg19
Start
46108101/45612653 (Hg38)
End
46108101/45612653 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA10G
Nearest miRNA
hsa-mir-1265/Upstream/448565; hsa-mir-107/Downstream/3372859;
Nearest TSS
ENST00000439456/Upstream/17747; ENST00000485850/Downstream/8274;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/17639, chr10-CpG: 78/Downstream/59576
Nearby gene
ZFAND4(No orient, 2848)
Nearest cancer related gene
ZFAND4(OG, No orient, 2848)
Upstream sequence
acctgatttatgcttacattaggctttggattttagactttagagttgatacttaaacaagttaagacttttagtgtggttgggatggaagagaatatat
Downstream sequence
ctacatgtgacaagaacacagattttggcaggccaCGGACAGTAtgttacagattgaacgcatgtgccccccacttcaaaattcccactttgaagcccta
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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