Basic Information
VIS ID
TVIS44017199
Fusion event
HTLV-1-FRMPD2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q11.22
Reference genome
GRCh37/hg19
Start
49474969/48266926 (Hg38)
End
49474969/48266926 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10G
Target gene
FRMPD2
Nearest miRNA
hsa-mir-1265/Upstream/3102838; hsa-mir-107/Downstream/718586;
Nearest TSS
ENST00000439456/Upstream/15169; ENST00000426557/Downstream/7641;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/126293, chr10-CpG: 127/Downstream/39362
Upstream sequence
tgtaagagagggtcagtacttttaccaccatgcagtggtaacaaggcatcccctgacgtgttgcatgaggagcagtaataaggtgtccccgaccctccta
Downstream sequence
gcaagggtggtgtcagcagaggactagaggggagccagaacagtcacaacaagatgccctcaaggttatcaagagagactgagtggggggtctagacttc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate