Basic Information
VIS ID
TVIS44017201
Fusion event
HTLV-1-DRGX integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q11.23
Reference genome
GRCh37/hg19
Start
50603182/49395136 (Hg38)
End
50603182/49395136 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10G
Target gene
DRGX
Nearest miRNA
hsa-mir-1265/Upstream/409549; hsa-mir-107/Downstream/1904437;
Nearest TSS
ENST00000439456/Upstream/95862; ENST00000423283/Downstream/315;
Nearest CpG islands
chr10-CpG: 263/Target, None/Upstream, None/Downstream
Upstream sequence
TTTGCTTTCTGGGATGTTTGCAGAAGCACCGTGAAAGATTGATGCGGCCCCCTGGGTTGCGGAGCCCCAATTAGAGGCGTGACACCAGCATCTGTGCTGG
Downstream sequence
GAGGATTCGGCCGGTCCCCGCGGCACGCCTAGCCCGGGGCGTCCTGGCCCAGGCGGGGAGGGAGCTGGGAGGCAGGTGGCGACGGGGCGGGGAGCTGGAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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