VISDB Viral Integration Site DataBase

VIS ID

TVIS44017213

Fusion event

HTLV-1-REEP3 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr10

Cytoband

q21.3

Reference genome

Start

End

65333617/63573857 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-374b-5p ; hsa-mir-590-3p ; hsa-mir-335-5p ; hsa-mir-375 ; hsa-mir-34a-5p ; hsa-mir-96-5p ; hsa-mir-93-5p ; hsa-mir-26b-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-106a-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519c-3p ; hsa-mir-526b-3p ; hsa-mir-519b-3p ; hsa-mir-519d-3p ; hsa-mir-519a-3p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-8066 ; hsa-mir-143-5p ; hsa-mir-1257 ; hsa-mir-3611 ; hsa-mir-4700-3p ; hsa-mir-8083 ; hsa-mir-190a-3p ; hsa-mir-548ao-5p ; hsa-mir-5011-5p ; hsa-mir-5585-5p ; hsa-mir-548ax ; hsa-mir-520g-5p ; hsa-mir-3941 ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-7703 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-542-3p ; hsa-mir-4252 ; hsa-mir-4299 ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-1292-3p ; hsa-mir-6849-3p ; hsa-mir-1273g-3p ; hsa-mir-508-5p ; hsa-mir-1273f ; hsa-mir-1273h-5p ; hsa-mir-139-3p ; hsa-mir-149-3p ; hsa-mir-30b-3p ; hsa-mir-30c-1-3p ; hsa-mir-30c-2-3p ; hsa-mir-3122 ; hsa-mir-3689a-3p ; hsa-mir-3689b-3p ; hsa-mir-3689c ; hsa-mir-3913-5p ; hsa-mir-450a-1-3p ; hsa-mir-4534 ; hsa-mir-4728-5p ; hsa-mir-4767 ; hsa-mir-6087 ; hsa-mir-6089 ; hsa-mir-6513-5p ; hsa-mir-6740-5p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-6785-5p ; hsa-mir-6788-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-7106-5p ; hsa-mir-8082 ; hsa-mir-887-5p ; hsa-mir-1294 ; hsa-mir-1914-3p ; hsa-mir-3184-5p ; hsa-mir-423-5p ; hsa-mir-4316 ; hsa-mir-4501 ; hsa-mir-4525 ; hsa-mir-4662a-5p ; hsa-mir-4716-3p ; hsa-mir-5010-5p ; hsa-mir-5194 ; hsa-mir-6734-5p ; hsa-mir-6738-5p ; hsa-mir-6794-5p

Nearest miRNA

hsa-mir-1265/Upstream/200809; hsa-mir-107/Downstream/3829494;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/51587, chr10-CpG: 69/Downstream/56258

Upstream sequence

AGGGGAAAAACATACTAAAGAACTTTTCTTTGTTCTCAAGAAGTGTTTCCTAGGTATCTTTTGATAATTTTGATAAAAAGTATTCATTTCATTTAAAGGT

Downstream sequence

TTTAATAATTTAGAAAGTTTAAAGATTAGCCTACTGATTATGATGGGATTTTTACTGAAAATTAGTTTTGTCAGGCTGCTTGCTTGTCTGTGTATTTTCT