VISDB Viral Integration Site DataBase

VIS ID

TVIS44017217

Fusion event

HTLV-1-SLC25A16 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr10

Cytoband

q21.3

Reference genome

Start

End

70267634/68507877 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-3149 ; hsa-mir-411-5p ; hsa-mir-6832-5p ; hsa-mir-29a-5p ; hsa-mir-4707-3p ; hsa-mir-4258 ; hsa-mir-6872-3p ; hsa-mir-510-3p ; hsa-mir-744-3p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-488-3p ; hsa-mir-4423-5p ; hsa-mir-6501-5p ; hsa-mir-6131 ; hsa-mir-3663-5p ; hsa-mir-1304-3p ; hsa-mir-4781-3p ; hsa-mir-4524a-3p ; hsa-mir-7703 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-661 ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-939-3p ; hsa-mir-6849-3p ; hsa-mir-1273g-3p ; hsa-mir-1228-3p ; hsa-mir-508-5p ; hsa-mir-129-5p ; hsa-mir-8055 ; hsa-mir-4309 ; hsa-mir-3198 ; hsa-mir-6805-3p ; hsa-mir-5691 ; hsa-mir-431-5p ; hsa-mir-4294 ; hsa-mir-1289 ; hsa-mir-3194-3p ; hsa-mir-8082 ; hsa-mir-4534 ; hsa-mir-924 ; hsa-mir-4708-5p ; hsa-mir-6088 ; hsa-mir-4770 ; hsa-mir-143-3p ; hsa-mir-6514-5p ; hsa-mir-1273f ; hsa-mir-92b-3p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-3689d ; hsa-mir-377-5p ; hsa-mir-4459 ; hsa-mir-455-3p ; hsa-mir-6086 ; hsa-mir-6134 ; hsa-mir-6499-3p ; hsa-mir-6516-5p ; hsa-mir-665 ; hsa-mir-6840-3p ; hsa-mir-6851-5p ; hsa-mir-6880-5p ; hsa-mir-7847-3p

Nearest miRNA

hsa-mir-1265/Upstream/1104467; hsa-mir-107/Downstream/3282870;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/35837, chr10-CpG: 41/Downstream/19326

Upstream sequence

ACTTTTGATCAAATATGAAAGGAAATCACCAGGTTCATTTCAAATTTTAGACTGCAAATAACCTCTTCAGCCCTTCTCAGTAATTAAAATTGTAGGTACT

Downstream sequence

TATTAACATCCAAAAGATATATCCCAAAAGCAGATATCGAAATGGACTAACATTCTGGTAAGAAGAATTCTggccttgcgtggtggctcatgcctgtaat