VISDB Viral Integration Site DataBase

VIS ID

TVIS44017225

Fusion event

HTLV-1-SFMBT2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr10

Cytoband

p14

Reference genome

Start

End

7405633/7363671 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-4743-3p ; hsa-mir-6888-3p ; hsa-mir-539-5p ; hsa-mir-7843-3p ; hsa-mir-4786-3p ; hsa-mir-6859-5p ; hsa-mir-3916 ; hsa-mir-3125 ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-5197-3p ; hsa-mir-7161-5p ; hsa-mir-548u ; hsa-mir-1178-3p ; hsa-mir-3972 ; hsa-mir-3194-5p ; hsa-mir-1202 ; hsa-mir-4722-5p ; hsa-mir-4524a-3p ; hsa-mir-4530 ; hsa-mir-4768-3p ; hsa-mir-4302 ; hsa-mir-761 ; hsa-mir-3619-5p ; hsa-mir-214-3p ; hsa-mir-648 ; hsa-mir-6165 ; hsa-mir-6868-3p ; hsa-mir-4263 ; hsa-mir-6499-3p ; hsa-mir-423-3p ; hsa-mir-631 ; hsa-mir-3661 ; hsa-mir-17-3p ; hsa-mir-598-5p ; hsa-mir-1248 ; hsa-mir-6893-3p ; hsa-mir-1237-3p ; hsa-mir-8079 ; hsa-mir-370-3p ; hsa-mir-1245a ; hsa-mir-4652-3p ; hsa-mir-616-3p ; hsa-mir-215-3p ; hsa-mir-6773-3p ; hsa-mir-4282 ; hsa-mir-1247-3p ; hsa-mir-1827 ; hsa-mir-185-5p ; hsa-mir-34b-3p ; hsa-mir-3614-5p ; hsa-mir-4306 ; hsa-mir-4644 ; hsa-mir-4649-3p ; hsa-mir-6500-3p ; hsa-mir-665 ; hsa-mir-6731-5p ; hsa-mir-6746-5p ; hsa-mir-6808-5p ; hsa-mir-6893-5p ; hsa-mir-7160-5p ; hsa-mir-8085 ; hsa-mir-940

Nearest miRNA

hsa-mir-3155a/Upstream/1211394; hsa-mir-107/Downstream/4767089;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/191530, chr10-CpG: 21/Downstream/3925

Upstream sequence

gcctgacctcgtgatccgcccgcatcggcctcccaaagtgctgtgattacaggcgtgagccaccacaccctgcctaaacctctttttctttataaattac

Downstream sequence

cagtctcaggtatgtctttattagcagtgtgagaacagactaatacccccctcatgcaaagatgagaaccccaagaaggggactcacccatggagctaag