VISDB Viral Integration Site DataBase

VIS ID

TVIS44017226

Fusion event

HTLV-1-FUT11 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr10

Cytoband

q22.2

Reference genome

Start

End

75536309/73776551 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-484 ; hsa-mir-331-3p ; hsa-mir-3648 ; hsa-mir-4503 ; hsa-mir-137 ; hsa-mir-18b-3p ; hsa-mir-5589-3p ; hsa-mir-25-3p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-92b-3p ; hsa-mir-6516-5p ; hsa-mir-4324 ; hsa-mir-455-3p ; hsa-mir-200a-3p ; hsa-mir-141-3p ; hsa-mir-548ad-3p ; hsa-mir-129-5p ; hsa-mir-505-3p ; hsa-mir-1290 ; hsa-mir-876-5p ; hsa-mir-3167 ; hsa-mir-6839-5p ; hsa-mir-378j ; hsa-mir-4714-3p ; hsa-mir-138-5p ; hsa-mir-4252 ; hsa-mir-4793-3p ; hsa-mir-4299 ; hsa-mir-766-3p ; hsa-mir-1273g-3p ; hsa-mir-1207-3p ; hsa-mir-508-5p ; hsa-mir-552-5p ; hsa-mir-607 ; hsa-mir-302c-5p ; hsa-mir-5696 ; hsa-mir-3143 ; hsa-mir-4729 ; hsa-mir-4698 ; hsa-mir-8063 ; hsa-mir-543 ; hsa-mir-186-5p ; hsa-mir-3133 ; hsa-mir-5047 ; hsa-mir-1301-3p ; hsa-mir-7156-3p ; hsa-mir-4753-3p ; hsa-mir-3124-3p ; hsa-mir-130b-5p ; hsa-mir-4691-3p ; hsa-mir-449b-3p ; hsa-mir-498 ; hsa-mir-6836-3p ; hsa-mir-5001-3p ; hsa-mir-675-5p ; hsa-mir-4466 ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-6778-3p ; hsa-mir-4695-3p ; hsa-mir-4772-3p ; hsa-mir-6787-3p ; hsa-mir-1304-3p ; hsa-mir-4726-3p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-6840-3p ; hsa-mir-6736-3p ; hsa-mir-6890-3p ; hsa-mir-1251-5p ; hsa-mir-1287-3p ; hsa-mir-3134 ; hsa-mir-3614-3p ; hsa-mir-4534 ; hsa-mir-5684 ; hsa-mir-6807-5p ; hsa-mir-7855-5p ; hsa-mir-8082 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-6514-5p ; hsa-mir-130a-3p ; hsa-mir-130b-3p ; hsa-mir-301a-3p ; hsa-mir-301b-3p ; hsa-mir-3135b ; hsa-mir-3613-3p ; hsa-mir-3652 ; hsa-mir-3666 ; hsa-mir-371a-5p ; hsa-mir-371b-5p ; hsa-mir-372-5p ; hsa-mir-373-5p ; hsa-mir-4295 ; hsa-mir-4430 ; hsa-mir-454-3p ; hsa-mir-4668-5p ; hsa-mir-500b-3p ; hsa-mir-616-5p ; hsa-mir-6879-3p

Nearest miRNA

hsa-mir-1265/Upstream/1055451; hsa-mir-107/Downstream/1775907;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/3492, chr10-CpG: 60/Downstream/5248

Nearby gene

FUT11(+333) ;

Upstream sequence

gaggccgaggagaggcgactgcttgaagccaggagtttgagaccatcctagcaagaccttgtctctaaaaaataaaagaattagcagggcatggtggtgc

Downstream sequence

acacctgtagccctagatacttgggaggttgaggcaggaggatcacttgagtccaggaatttaaggctgcaatgagctatgatcatgatcactgcactcc