Basic Information
VIS ID
TVIS44017233
Fusion event
HTLV-1-BMS1P21 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
81690929/79931173 (Hg38)
End
81690929/79931173 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA10D
Target gene
BMS1P21
Nearest miRNA
hsa-mir-1265/Upstream/4378620; hsa-mir-107/Downstream/6333521;
Nearest TSS
ENST00000439456/Upstream/89815; ENST00000608229/Downstream/17930;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/25853, chr10-CpG: 110/Downstream/50299
Upstream sequence
CTCCCAACCATGGCTGAGATGGAGGGGAAGGTGATGAGACATGGTTTAACATCACACTCACTGTTATATGGTCGTGCTTGCCTAATGCACCAAGATTATG
Downstream sequence
AGCTAAATTCCACATCAGATAAAAAGCAGTGCCGCTTTCCTCCTCAGCCAGGGAGATGTAAACCACCTGGAGCTTCAGGGCAAGGAGTGTAAAATCTGAC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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