Basic Information
VIS ID
TVIS44017237
Fusion event
HTLV-1-chr10 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
85918059/84158303 (Hg38)
End
85918059/84158303 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA10D
Nearest miRNA
hsa-mir-1265/Upstream/8605750; hsa-mir-107/Downstream/2106391;
Nearest TSS
ENST00000439456/Upstream/17721; ENST00000472542/Downstream/15435;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/18419, chr10-CpG: 85/Downstream/36140
Nearby gene
GHITM(+4748) ;
Upstream sequence
GGATGAATGGCTGGAAACCCATCATTCTAGAAGACAGCATCCAATGAGCAGTGGGAGTGGGTAGTTGCTAGGAGGATCTAATTCTAGAGAGAGAAGGCAG
Downstream sequence
TGCTGGAGGCAGAAGCCTTTACTGTGGGTGGGGAATGTTAATCATTAGAAGCCACTGTTTTAAGAGATTAAATCAACATTTATTAGACACTCTAAAGTAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate