Basic Information
VIS ID
TVIS44017238
Fusion event
HTLV-1-LOC105378415 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q23.31
Reference genome
GRCh37/hg19
Start
89835187/88075430 (Hg38)
End
89835187/88075430 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10D
Target gene
LOC105378415
Nearest miRNA
hsa-mir-1265/Upstream/571476; hsa-mir-107/Downstream/987905;
Nearest TSS
ENST00000439456/Upstream/123231; ENST00000526923/Downstream/507760;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/211102, chr10-CpG: 61/Downstream/507341
Nearby gene
PTEN(+103500) ;
Upstream sequence
ttctgtgccttggttttctcatcagtagagtaagaatataatcagtcttcacatgatgtgaggctgaaacaagttaatacattttaaatgcttagaaagg
Downstream sequence
tacctggcaaacattcagctctatttattgtttgttattTTATTAAAAATAAAATGAATGTTATCGATGGACATGGGTgagaagcagtgaggagtagaaa
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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