VISDB Viral Integration Site DataBase

VIS ID

TVIS44017246

Fusion event

HTLV-1-CPEB3 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr10

Cytoband

q23.32

Reference genome

Start

End

94005428/92245671 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-26a-5p ; hsa-mir-29a-3p ; hsa-mir-23b-3p ; hsa-mir-196a-5p ; hsa-mir-21-5p ; hsa-mir-320a ; hsa-let-7b-5p ; hsa-mir-8485 ; hsa-mir-513a-3p ; hsa-mir-513c-3p ; hsa-mir-3606-3p ; hsa-mir-205-5p ; hsa-mir-3978 ; hsa-mir-6124 ; hsa-mir-3148 ; hsa-mir-922 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-3714 ; hsa-mir-548an ; hsa-mir-548e-5p ; hsa-mir-5047 ; hsa-mir-1301-3p ; hsa-mir-7156-3p ; hsa-mir-103a-3p ; hsa-mir-107 ; hsa-mir-25-3p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-32-5p ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-6873-3p ; hsa-mir-377-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-342-3p ; hsa-mir-4328 ; hsa-mir-548au-3p ; hsa-mir-449b-5p ; hsa-mir-449a ; hsa-mir-34c-5p ; hsa-mir-34a-5p

Nearest miRNA

hsa-mir-107/Upstream/2652844; hsa-mir-1287/Downstream/3818644;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/5427, chr10-CpG: 99/Downstream/44995

Upstream sequence

TATTTCCCATTTTTTCTCTTCCTCTAGCCTCCTAAAGAAAGCTCCACTTTTGCCAAGGTGCTGTGGTCACTATTTGGATTCCAAAATTTGCAAGGATCAA

Downstream sequence

CCCAAGGTTAATGTTATTCCTGAAGACTTTGCTAACCTACCAAACTTTTGCCACATTTTCAAGTATTCTAACTAAAATAAAATAgccgggcacggtggct