Basic Information
VIS ID
TVIS44017257
Fusion event
HTLV-1-chr11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
101758422/101887691 (Hg38)
End
101758422/101887691 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10392/Upstream/367786; hsa-let-7a-2/Downstream/1962215;
Nearest TSS
ENST00000527297/Upstream/15129; ENST00000532529/Downstream/20243;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/303738, chr11-CpG: 54/Downstream/27172
Nearby gene
ANGPTL5(-2983) ;
Upstream sequence
gaactcaacctggatgacaccttgatttagccccatcattctctgagcagagaacgcacacaacctttgccagacttctgagtttcaaaactgtaagcta
Downstream sequence
atagttgagagtccttttaagccactaaatttgtggtaatctgtcacgcagcaataaaaaactaataTGTTTGTAGTATACTTTCACAACCAATATATCA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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