Basic Information
VIS ID
TVIS44017268
Fusion event
HTLV-1-LOC107984390 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
113501340/113630618 (Hg38)
End
113501340/113630618 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11G
Target gene
LOC107984390
Nearest miRNA
hsa-mir-10392/Upstream/180530; hsa-let-7a-2/Downstream/5013382;
Nearest TSS
ENST00000527297/Upstream/154927; ENST00000453129/Downstream/63119;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/155012, chr11-CpG: 37/Downstream/142959
Nearby gene
TMPRSS5(-56928) ;
Upstream sequence
AGTGGCCCCCAGACCACTAGGCTGTCACTGAAGTTGATGCCTTTCCTACAGGGACAAGGAACCCAGCAGACCTGCCTCCTGCCTCGTTCTGCCACCTGGG
Downstream sequence
GAAGGCAGGGTTCTGCCTTTGAGCCTAAAGAGTTTTCTACCCCAGGGCTGAGAGTGTGAGTGGAAGTCAGGAGGAACCAGCTCTAGGTAAAGCCCTAGGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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