Basic Information
VIS ID
TVIS44017271
Fusion event
HTLV-1-LOC105369506 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
114702940/114832218 (Hg38)
End
114702940/114832218 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA11G ; FRA11B
Target gene
LOC105369506
Nearest miRNA
hsa-mir-10392/Upstream/1382130; hsa-let-7a-2/Downstream/3811782;
Nearest TSS
ENST00000527297/Upstream/153832; ENST00000545593/Downstream/346893;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/392354, chr11-CpG: 26/Downstream/128817
Nearby gene
NXPE2(No orient, 125288)
Upstream sequence
CGGTGGGCACCAGCATTAAGGAGGAAATGATTTTCTTTCATCTGTCCAAGTAAATCTTTCCCCAACACTTGTCAAGCTGATTGCTGCCAATTTCCAGCTA
Downstream sequence
GAGAAACACAGCCATTTAGACGGGGAGACATTAGTAACTAGAAGATACTTACAACATTTAAAACGGGGCTTTGCCttttcctttttttttttttcttcag
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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