VISDB Viral Integration Site DataBase

VIS ID

TVIS44017284

Fusion event

HTLV-1-CD3D integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr11

Cytoband

q23.3

Reference genome

Start

End

118213045/118342330 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-7977 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-342-3p ; hsa-mir-383-3p ; hsa-mir-1228-3p ; hsa-mir-5588-3p ; hsa-mir-2114-5p ; hsa-mir-3180-5p ; hsa-mir-3160-5p ; hsa-mir-372-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-5699-3p ; hsa-mir-4421 ; hsa-mir-339-5p ; hsa-mir-370-3p ; hsa-mir-6893-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6740-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-3622b-5p ; hsa-mir-4530 ; hsa-mir-6773-5p ; hsa-mir-6724-5p ; hsa-mir-6508-3p ; hsa-mir-4726-5p ; hsa-mir-4640-5p ; hsa-mir-4755-3p ; hsa-mir-4673 ; hsa-mir-4645-5p ; hsa-mir-10a-5p ; hsa-mir-10b-5p ; hsa-mir-1272 ; hsa-mir-3926 ; hsa-mir-4684-5p ; hsa-mir-4786-5p ; hsa-mir-548c-3p ; hsa-mir-548s ; hsa-mir-593-3p ; hsa-mir-6732-3p ; hsa-mir-6818-3p ; hsa-mir-6849-3p ; hsa-mir-6895-3p

Nearest miRNA

hsa-mir-10392/Upstream/4892242; hsa-let-7a-2/Downstream/301670;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/188851, chr11-CpG: 22/Downstream/17119

Upstream sequence

catgatcacagctcactgaagccttgaaatcccgggctcaagtgaccctcctgcctcagcctctcaaatagctgggactacagttgtgcaccaccatgcc

Downstream sequence

tggctaattcttttgttttttgtaaagatagagtctcatcatgttgctcagactggtctcaaactcctggcctcaaaggatcctcccacttcggcctccc