Basic Information
VIS ID
TVIS44017290
Fusion event
HTLV-1-chr11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
122509418/122638710 (Hg38)
End
122509418/122638710 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7a-2/Upstream/486402; hsa-mir-3167/Downstream/742730;
Nearest TSS
ENST00000527297/Upstream/336947; ENST00000525711/Downstream/16965;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/1186117, chr11-CpG: 113/Downstream/16860
Nearby gene
UBASH3B(+16980) ;
Upstream sequence
GATATTAACAATAGGCAAAGAGCTGTCCTCCCCAGGTTTTAATGAGTAGAAATAAGAAAACTCAGGGATTCGGAGGTAGATGAGCCTGGACTGTATTTTC
Downstream sequence
ACCTGTACCTATTTTGTTTTCCCTTTTTCTTTCCCGTCTCCCATTCTAATTCCAGTATTACTGGTAGTTAGCGAGTTAGCTAGACCCAAGTCCATTGTAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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