Basic Information
VIS ID
TVIS44017300
Fusion event
HTLV-1-LOC105369574 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
130401925/130532030 (Hg38)
End
130401925/130532030 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105369574
Nearest miRNA
hsa-let-7a-2/Upstream/2009581; hsa-mir-4697/Downstream/134705;
Nearest TSS
ENST00000527297/Upstream/83056; ENST00000317019/Downstream/140926;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/58273, chr11-CpG: 20/Downstream/14875
Nearby gene
ADAMTS15(+55386) ;
Upstream sequence
AGTGAGTGTGTTGTTGGAAACACAAAGAAGCCAAGCTGAATGCCGCCCGAGGCACTAAGCTAGTGGTAGCTCCAGCAAATCCCCAGGATGATGTTGGTGT
Downstream sequence
ATACATGGCATGGAAAGACTTCAGGTCACCACCAGTGCCCTCAAAAGTCCATTTTCTGACACTAAGCCCAATGATTTGCTCTTTTTGCCCCTGCCTCCGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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