Basic Information
VIS ID
TVIS44017332
Fusion event
HTLV-1-chr11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p13
Reference genome
GRCh37/hg19
Start
32515723/32494177 (Hg38)
End
32515723/32494177 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA11E
Nearest miRNA
hsa-mir-210/Upstream/4016629; hsa-let-7a-2/Downstream/2447660;
Nearest TSS
ENST00000527297/Upstream/58547; ENST00000532054/Downstream/89621;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/54908, chr11-CpG: 64/Downstream/89460
Nearby gene
WT1-AS(+35408) ;
Upstream sequence
aataccatttccattttgtagaagttaaataacttgcccaaagtcacacagctggtgaagctgggctttgaccacaggcattatatctcccgagtctgtg
Downstream sequence
cgctaagctccaatattaaactACTACTATTGTTAATAATTAATTAAATGTTGTTCAGTAGATTTTCTGCTGGAAATGTAAGGGTTAACAACTCTGAAGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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