Basic Information
VIS ID
TVIS44017350
Fusion event
HTLV-1-TTC17 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
43434749/43413199 (Hg38)
End
43434749/43413199 (Hg38)
Orient
-
Location type
Intronic
Target gene
TTC17
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-16-5p
Nearest miRNA
hsa-mir-1343/Upstream/7402995; hsa-let-7a-2/Downstream/146457;
Nearest TSS
ENST00000527297/Upstream/9147; ENST00000534417/Downstream/23023;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/53709, chr11-CpG: 20/Downstream/109086
Upstream sequence
ttaaaagagtatggtattggtacaaagatactcaaacatagcaatggaacataatagggaatttagaagtagaccaccatgaatatggccactggtttat
Downstream sequence
gacaaaggggtacctgtagttcagtgaggaaaaaacattttggtttttcagtaagttagtgctagaataattggatgatatccttatggagaaagataag
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate