Basic Information
VIS ID
TVIS44017359
Fusion event
HTLV-1-chr11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
48365768/48344216 (Hg38)
End
48365768/48344216 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-129-2/Upstream/247358; hsa-let-7a-2/Downstream/8399657;
Nearest TSS
ENST00000527297/Upstream/18864; ENST00000446524/Downstream/22249;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/362598, chr11-CpG: 17/Downstream/535929
Nearby gene
OR4C45(No orient, 1132)
Upstream sequence
agaccagatgagaaatcaagtctgtttgatccaaggctcttAATCCCTAACTTCAAAACGTCTGACTATATCTGAATCTTTTAACATTTCATTACATTCT
Downstream sequence
TGGTATGGATTCTTTTCTATGATCTACATTTGTGATCACCATCATCCAGTTTCATGATACAAACTTATTTCTACATCTCTGGTAATTTCCTTTTCAGCTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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