Basic Information
VIS ID
TVIS44017365
Fusion event
HTLV-1-LOC105369315 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
58872849/59105376 (Hg38)
End
58872849/59105376 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105369315
Nearest miRNA
hsa-mir-129-2/Upstream/1464090; hsa-let-7a-2/Downstream/489701;
Nearest TSS
ENST00000527297/Upstream/19069; ENST00000528234/Downstream/1809;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/2773, chr11-CpG: 49/Downstream/1040
Nearby gene
FAM111B(+1809) ;
Upstream sequence
aaaagcccaggaatcgtcattgagccctctgtttctcttatttatggaacatccataagcaaattccaagggctggcccttcaaaataaatgtggaatcc
Downstream sequence
agccatttctaacacttccaccattaccatctgaggtcgggctccaacatctttgcaatcctgggacagactcttagctgccttctcccttccacatctc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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